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Candesartan Excipients

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Candesartan Excipients Specification

Molecular Weight
610.67 g/mol

Acid Value
< 0.5 mg KOH/g

Moisture (%)
0.5%

Loss on Drying
0.5%

HS Code
29420090

Melting Point
162 - 166C

Molecular Formula
C33H34N6O6

Residue on Ignition
0.1%

Place of Origin
India

Ph Level
Between 5.0 7.5

Particle Size
90% < 150 micron

Assay
>99%

Storage
Store in cool, dry place

Heavy Metal (%)
0.001%

EINECS No
689299-90-9

Other Names
Candesartan Cilexetil Excipients

CAS No
139481-59-7

Type
Pharmaceutical Excipient

Grade
Pharmaceutical Grade

Usage
Used as a carrier or diluent for Candesartan tablet formulation

Purity
99% min

Appearance
Powder

Application
Pharmaceutical Industry

Raw Material
Candesartan Active Ingredients

Smell
Odorless

Color
Colorless

Form
Solid

Regulatory Compliance
Complies with ICH Q7 guidelines

Solubility
Practically insoluble in water, freely soluble in methanol and ethanol

Reactivity
Stable under recommended conditions

GMO Status
Non-GMO

Allergen Information
Allergen free

Microbial Limit
Total aerobic microbial count < 100 cfu/g

Identification
Conforms to USP specification

Packaging
HDPE drums with double polyethylene bags, 25 kg packing

TSE/BSE Status
Free from TSE/BSE risk

Shelf Life
36 months from date of manufacture

Candesartan Excipients Trade Information

FOB Port
NHAVASHEVA

Payment Terms
Cash in Advance (CID), Letter of Credit at Sight (Sight L/C), Telegraphic Transfer (T/T), Letter of Credit (L/C)

Supply Ability
10000 Per Month

Delivery Time
6 Week

Sample Available
Yes

Sample Policy
Free samples available with shipping and taxes paid by the buyer

Packaging Details
OFFERED IN EXPORT WORTHY PACKING OF 25 KILOS OR AS PER OUR CUSTOMER REQUIREMENTS

Main Export Market(s)
Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Main Domestic Market
All India, South India, Central India, West India, North India, East India, Gujarat, Karnataka, Kerala, Lakshadweep, Mizoram, Meghalaya, Manipur, Andhra Pradesh, Bihar, Chandigarh, Daman and Diu, Goa, Jharkhand, Odisha, Punjab, Assam, Delhi, Dadra and Nagar Haveli, Andaman and Nicobar Islands, Arunachal Pradesh, Chhattisgarh, Haryana, Himachal Pradesh, Jammu and Kashmir, Madhya Pradesh, Maharashtra, Nagaland, Rajasthan, Sikkim, Tamil Nadu, Telangana, Tripura, Pondicherry, Uttar Pradesh, Uttarakhand, West Bengal

Certifications
FDA

About Candesartan Excipients

Candesartan is an angiotensin 2 receptor blocker. The mechanism of action of candesartan is as an angiotensin 2 receptor antagonist.

Candesartan is a synthetic, benzimidazole-derived angiotensin ii receptor antagonist prodrug with antihypertensive activity. candesartan selectively competes with angiotensin ii for the binding of the angiotensin ii receptor subtype 1 (at1) in vascular smooth muscle, blocking angiotensin ii-mediated vasoconstriction and inducing vasodilatation. In addition, antagonism of at1 in the adrenal gland inhibits angiotensin ii-stimulated aldosterone synthesis and secretion by the adrenal cortex; sodium and water excretion increase, followed by a reduction in plasma volume and blood pressure.