ARTESUNATE Excipients

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ARTESUNATE Excipients Specification

Molecular Weight
384.40 g/mol

Particle Size
200 mesh

Molecular Formula
C19H28O8

HS Code
29329990

Moisture (%)
0.5% Max

Assay
99% Min

Residue on Ignition
0.1% Max

Loss on Drying
0.5% Max

Heavy Metal (%)
0.001% Max

Melting Point
135-140 C

Place of Origin
India

Storage
Cool, dry place

Other Names
Dihydroartemisinin-10-b-succinate

CAS No
88495-63-0

Type
Excipients

Grade
Pharmaceutical Grade

Usage
Used as an antimalarial raw material

Purity
99% Min

Appearance
Fine Powder

Application
Pharmaceutical Industry

Raw Material
Yes

Smell
Odorless

Color
White

Form
Powder

ARTESUNATE Excipients Trade Information

Payment Terms
Letter of Credit at Sight (Sight L/C), Telegraphic Transfer (T/T)

Packaging Details
OFFERED IN EXPORT WORTHY PACKING OF 25 KILOS OR AS PER OUR CUSTOMER REQUIREMENTS

Main Export Market(s)
Australia, North America, Eastern Europe, Western Europe, Africa, Central America, Middle East, South America, Asia

About ARTESUNATE Excipients

Artesunate is a water-soluble, semi-synthetic derivative of the sesquiterpine lactone artemisinin with anti-malarial, anti-shistosomiasis, antiviral, and potential anti-neoplastic activities. Upon hydrolysis of artesunate's active endoperoxide bridge moiety by liberated heme in parasite-infected red blood cells, reactive oxygen species and carbon-centered radicals form, which have been shown to damage and kill parasitic organisms. Additionally, in vitro studies demonstrate that this agent induces dna breakage in a dose-dependent manner. Artesunate has also been shown to stimulate cell differentiation, arrest the cell cycle in the g1 and g2m phases, inhibit cell proliferation, and induce apoptosis through mitochondrial and caspase signaling pathways. Artemisinin is isolated from the plant artemisia annua. Artesunate is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection.

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